Opened powder can be refrigerated for up to 3 months, or can be frozen for up to 6 months to preserve freshness. Warning: This product is intended for intermittent or supplemental feeding only. Not for human consumption. « Read less . Esbilac(R) Puppy Milk Replacer Esbilac Puppy Milk Replacer has been saving the lives of puppies for over 50 years.